Chargement de la page
Logo of D.E.S is it, DES Action group in France (Diethylstilbestrol)


H.G Wells, The Island of Doctor Moreau

Organization for Defending all Generations of Victims of DES

Distilbène ointment (diethylstilbestrol) against vulvar and anogenital pruritus, juvenile acne, eczema, hypertrichosis, by M Borne laboratories - Join D.E.S is it, the patient association for diethylstilbestrol victims

Diethylstilbestrol (or D.E.S.) is a synthetic teratogenic estrogen. In France, the drug has been marketed under the brand names Distilbène®, Stilboestrol-Borne® and Furostilboestrol®. It was widely prescribed to pregnant women between 1948 and 1977, mainly to prevent miscarriage, premature labor and related complications of pregnancy.

Because of an aggressive and effective marketing, a low-cost production and very lucrative profits, D.E.S has been prescribed while its carcinogenic properties were already questioned, and continued to be prescribed after 1971, when its toxicity has been clearly proven.

D.E.S has been shown to cause anatomic anomalies, sterility, reproductive changes and increase the risk of developing cancers in children exposed in utero (so-called "DES children", or second-generation patients). Due to a transgenerational effect, their children are also affected (so-called "DES grandchildren" or third-generation patients).

This endocrine disruptor has caused much more various less visible damages: mental disorders, behavioral disorders, neurodevelopmental disorders, endocrine disorders, etc.

This prenatal exposure to DES has led to the definition of a rare disease: Diethylstilbestrol syndrome (or Distilbene embryofoetopathy).

Join DES is it, the association of patients affected by diethylstilbestrol (DES, Distilbene, Stilbestrol).

At present, patients exposed to DES are in medical limbo. And for good reason: as there is no associated Reference Centre, none can be diagnosed with Diethylstilbestrol Syndrome. There is no diagnostic protocol, no care protocol, no treatment, nothing.

What's more, since Diethylstilbestrol Syndrome was first defined, scientific studies have revealed far more far-reaching consequences, justifying its updating.

We are making it our priority to resolve these shortcomings.

D.E.S is it, also means providing moral support to families who have suffered, helping them to understand their rare disease and defending their cause in terms of the medical care to which they should be entitled.

Logo of D.E.S is it, DES Action group in France (Diethylstilbestrol) tEAM

Stay tuned to our actions

Stay tuned to D.E.S is it actions! Subscribe to our newsletter!

Support Us

Donate to French Group D.E.S is it

Latest news

Prenatal exposure to synthetic sex hormones – including diethylstilbestrol – as a risk factor for autism spectrum disorders

Prenatal exposure to synthetic sex hormones – including diethylstilbestrol – as a risk factor for autism spectrum disorders

DES (a widespread abbreviation for diethylstilbestrol, a synthetic estrogen), has been marketed in the 1950s in many countries by different pharmaceutical companies (UCB Pharma, Borne, Eli Lilly...), under different brand names (Distilbene®, Stilboestrol-Borne®, Furostilboestrol®...) This drug, advertised as a new "miracle drug&...

Read more

Resilience: a scientist's campaign against synthetic hormones – Marie-Odile Soyer-Gobillard's testimonial

Like many women between 1949 and 1970 (in France), Marie-Odile Soyer-Gobillard, after having a miscarriage, was prescribed a "miraculous" treatment that was supposed to guarantee the success of her subsequent pre...

Read more

Effects of in utero diethylstilbestrol exposure on the pancreas

DES (diethylstilbestrol) is a synthetic estrogen and notorious endocrine disruptor synthesized in 1938 by a group of English scientists led by E.C. Dodds. It has been marketed in many countries by different pharmaceutical ...

Read more
Contact Us

The file must be a file of type pdf, doc, docx, odt or jpg and not exceed 2MB (megabyte)

Accept This form uses Google ReCaptcha. Before sending the form, please accept cookies.
* Required Fields